An optimized13C-urea breath test for the diagnosis ofH pyloriinfection

The urea breath test for Helicobacter pylori.

An optimized 13C-urea breath test for the diagnosis of H pylori infection.

AIM To validate an optimized (13)C-urea breath test ((13)C-UBT) protocol for the diagnosis of H pylori infection that is cost-efficient and maintains excellent diagnostic accuracy. METHODS 70 healthy volunteers were tested with two simplified (13)C-UBT protocols, with test meal (Protocol 2) and without test meal (Protocol 1). Breath samples were collected at 10, 20 and 30 min after ingestion ...

[Validation of a simplified 13C-urea breath test method for the diagnosis of Helicobacter pylori infection].

OBJECTIVE To validate a simplified 13C-urea breath test (13C-UBT) method for the diagnosis of H. pylori infection. MATERIAL AND METHODS Patients referred for gastrointestinal endoscopy and biopsy were included, and a 13C-UBT was performed after a 6-hour fast. Breath samples were collected in 10 ml glass tubes before and 30 min after the simultaneous administration of 50 mg of 13C-urea and 2 g...

Low dose capsule based 13c-urea breath test compared with the conventional 13c-urea breath test and invasive tests.

CONTEXT One of the limitations of 13C-urea breath test for Helicobacter pylori infection diagnosis in Brazil is the substrate acquisition in capsule presentation. OBJECTIVES The purpose of this study was to evaluate a capsule-based 13C-urea, manipulated by the Pharmacy Division, for the clinical practice. METHODS Fifty patients underwent the conventional and the capsule breath test. Samples...

The 13C urea breath test in the diagnosis of Helicobacter pylori infection.

The urea breath test (UBT) is one of the most important non-invasive methods for detecting Helicobacter pylori infection. The test exploits the hydrolysis of orally administered urea by the enzyme urease, which H pylori produces in large quantities. Urea is hydrolysed to ammonia and carbon dioxide, which diffuses into the blood and is excreted by the lungs. Isotopically labelled CO2 can be dete...